Protein Structure Stellenangebote

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43 Stellenangebote

Stellenangebote Protein Structure Jobs bei Jobleads

Job vom 06.11.2024

Principal Research Scientist II, AI/ ML Team Lead

• Ludwigshafen am Rhein, Rheinland- Pfalz Führungs-/ Leitungspositionen

MEHR

[...] a multifunctional, global organization that drives computational approaches to small molecule drug discovery, supporting all therapeutic areas. The mission of this organization is to apply state- of- the- art computational chemistry, machine learning and physics- based methods to better understand protein structure/ function and to accelerate the drug discovery process from hit generation to clinical candidate selection. We are making significant investments [...]
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Job vor 2 Tagen gefunden Lead Computational Chemist/ Molecular Modeller • Berlin Führungs-/ Leitungspositionen

MEHR

[...] system small- molecule therapeutics are nature- inspired with less than 1 of natures small molecules having been mapped and explored. Our lead R D program focuses on the TrkB receptor pathway, which drives neuronal survival, synaptic plasticity and reduces pathological protein aggregates. Our first candidate molecule will enter clinical trials in 2025. Pangea Bios AI engine enables us to study the [...] limited to) : Understanding project requirements for the discovery of novel active ingredients in different therapy areas, with a focus on CNS and dermatology. Develop and apply both ligand- based/ ML models for compound prioritization and optimisation, as well as structure- based methods, with a focus on a holistic compound profile (including on- target and off- target effects, as well as [...]

Job vor 3 Tagen gefunden

Scientist Medicinal Chemistry (m/f/d)

• Hamburg, Berlin Jobticket

MEHR

[...] and physicists, and you will contribute to shaping and implementing the chemical and bio- physical activities in the areas of hit identification, hit expansion/ refinement, as well as lead identification. From the target characterization department, you obtain validated cancer treatment protein targets for which biochemical and biophysical screening assays have been established. Within the group, you have the following tasks: Contribute to Medicinal Chemistry/ overall project related strategies for innovative drug discovery projects from hit identification through to candidate nomination. Structure- based compound identification:- Prepare protein targets for virtual ligand screening- Select libraries for virtual screening- Prepare the ligands for virtual [...]

Job vor 7 Tagen gefunden Scientist Biochemistry (all genders) • Frankfurt, Hesse

MEHR

[...] agro and pharma, investigating novel targets for herbicide discovery using both in- vitro and in- vivo techniques. Part of your role is to be familiar with and to develop new computational technologies, such as comparative genomics, molecular modeling, or biomolecule structure prediction, to identify herbicide targets. You utilize biochemistry techniques like protein expression and purification, enzyme kinetics, and develop biochemical assays to characterize herbicide targets. Designing and executing experiments in the laboratory [...]

Job vor 7 Tagen gefunden

SPR Senior Scientist

• Martinsried, Bayern

MEHR

CRELUX, part of the Wu Xi App Tec Discovery Biology unit, is a global provider of structure based drug discovery solutions. We have been delivering customized and integrated services in drug discovery, X- ray crystallography, protein supply, biophysical analysis and fragment screening, to support small and large molecule, as well as biopharmaceutical drug discovery, for more [...]

Job vor 13 Tagen gefunden Research Scientist (gn) Protein Sciences with focus on membrane proteins • München, Bayern

MEHR

YOUR MISSION Contribution to multidisciplinary teams with own scientific expertise to achieve corporate and customer goals of challenging drug discovery projects Independent planning and execution of research projects within the field of membrane proteins (GPCRs) Development, implementation and optimization of protein production workflows for membrane proteins (with focus on GPCRs) Evaluation of new technology and/ or equipment to constantly improve the [...] Presentation of the scientific results as well as convincing and confident communication of the content to colleagues, customers, and business partners YOUR PROFILE PhD in biochemistry or related field with an excellent proven track record Strong acquaintance with regard to structure- based construct design, expression and purification of GPCRs Profound knowledge in structural biology (Xray and/ or cryoEM) is a plus [...]
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Job vor 13 Tagen gefunden

Aachen: Stellvertretung der Leitung der Herstellung (m/w/d) Pharma

• Aachen, Nordrhein- Westfalen Führungs-/ Leitungspositionen Beratungs-/ Consultingtätigkeiten

MEHR

[...] cleaning procedures Conducting employee training sessions Reviewing manufacturing instructions and reports Collaborating with the Regulatory Affairs department to prepare regulatory documents Maintaining the document management system Degree in Chemistry, Biology, Biotechnology, or Pharmacy Experience in the (bio) pharmaceutical field (fermentation, protein purification) is preferred Strong initiative, conceptual, and analytical skills Excellent proficiency in both English and German, spoken and written Good IT skills (MS Office, electronic document management systems, equipment software) Knowledge of GMP or other regulated environments What the company offers: A challenging and diverse role where you can take responsibility and grow as a leader A flat organizational structure in a stable family- owned company Collaborative, team- oriented work environment Regular training and further development to maintain up- to- [...]
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Job vom 09.11.2024 Technical Assistant position in the Orts lab Vienna • Wien Beratungs-/ Consultingtätigkeiten

MEHR

[...] Chemistry at the University of Vienna. The 20- hour position should ideally start as soon as possible and is limited to 3 years. The Orts lab is focusing on Drug Discovery by advanced NMR methods, including integrated methods for fast protein- ligand complex structure determination, NMR based drug design, protein allostery, and thermodynamics of protein- protein and protein- ligand interactions. We apply these techniques [...]
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Job vom 08.11.2024

PhD Position in Structural Biology Nuclear Receptors

• München, Bayern

MEHR

[...] motivated PhD candidate to join our team in the Department of Pharmacy. This PhD project aims to uncover the molecular details of nuclear receptor interactions with small- molecule ligands to support therapeutic development. The primary techniques involved will include recombinant protein expression and purification, crystal growth, X- ray data collection, and structure elucidation. Additional methods will encompass biophysical measurements of binding affinities (e. g. , BLI, ITC) and biochemical assays (e. g. [...]
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Job vom 07.11.2024 Cryo- Electron Microscopy Specialist EMBL Imaging Centre • Heidelberg, Baden- Württemberg

MEHR

[...] is currently constructing the EMBL Imaging Centre to make the latest imaging technologies available as quickly as possible to a broad, international user community of researchers from academia to industry. A broad spectrum of imaging technologies covering the scales from structure determination of single protein complexes to imaging whole organisms will be offered, with a special emphasis on cross modality capabilities (correlative microscopy) and bespoke [...]

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